Leukopenia: decrease in the number of white blood cells in the blood

Leukopenia is a low number of white blood cells in the body. This can occur due to several factors. Discover various conditions or diseases that cause a decrease in the number of white blood cells.

Blood consists of platelets, blood plasma, red blood cells and white blood cells. Each component of the blood has its own function, including white blood cells, which are an important part of our immune system. White blood cells, also called leukocytes, act against foreign objects or organisms that enter the body by producing antibodies to fight infection. If leukopenia occurs, i.e. the white blood cell count is too low, we will be susceptible to disease.

The condition causes low white blood cells
White blood cell examination is part of a complete blood test. Doctors usually ask for this test to establish a diagnosis or assess certain conditions. Did you know that in blood microliters, there are usually 3,500 to 10,500 white blood cells? Leukopenia is called if the white blood cell count is less than 4,000. This shows the existence of certain disorders or diseases in our body.

Low white blood cell count or leukopenia is usually caused by:

  • Infection, for example in cases of sepsis, HIV / AIDS and tuberculosis.
  • Congenital birth defects cause a decrease in bone marrow function in the production of blood cells, such as myelokathexis and Kostmann's syndrome.
  • Autoimmune disorders that destroy white blood cells or bone marrow cells, such as lupus and arthritis (rheumatoid arthritis).
  • Severe infections that make white blood cells even further away.
  • Some drugs, such as antibiotics that damage white blood cells, chemotherapy, penicillin or corticosteroids.
  • Leukopenia or lack of white blood cells can be caused by a deficiency of vitamin B12, folate, zinc and copper.
  • There are abnormalities or diseases related to blood cells or bone marrow, such as aplastic anemia, hypersplenism or overactive spleen, myelodisplastic syndrome (MDS), myeloproliferative abnormalities, and myelofibrosis.
  • Blood cancer and bone marrow cancer. Namely cancer that develops in the bone marrow and prevents blood cells from developing and developing normally.
  • Cancer multiplication or metastasis. Cancer cells can spread to other organs or tissues, including bone marrow, and affect their function. As a result, the bone marrow has difficulty producing blood cells that the body needs.
  • Radiotherapy. Radiation therapy to large bones that contain the most bone marrow, such as the pelvis, legs, and chest, makes leucopenia vulnerable.

Sarcoidosis, a systemic disease caused by an excessive immune response and is characterized by granuloma formation or inflammation in several body systems. If granulomas form in the bone marrow, leukopenia can occur.

Low leukocytes or leukopenia often occur without symptoms, but if you experience fever, cold, or weight loss for no known reason, seek immediate medical help for further tests.

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