Peyronie's disease

Peyronie's disease is a condition characterized by obvious penile flexion, usually upward or sideways. This condition is caused by the formation of fibrous plaque or scar tissue along the shaft of the penis. Changes in the shape of the penis will be seen clearly when erect.

Peyronie's disease
Peyronie's disease can be experienced by all men of various ages. However, most victims are middle-aged men. An estimated 3 to 9% of men in the world suffer from Peyronie's disease.

Not yet known for sure the cause of the formation of scar tissue in the shaft of the penis. However, it is suspected he began to experience bleeding due to trauma or injury. In addition, it has also been suspected that the formation of scar tissue is caused by genetic factors inherited from the family.
Symptoms of Peyronie's disease

Symptoms of Peyronie's disease can appear suddenly or develop gradually, including:

  • Curved penis shape. The penis can be bent up, down or to one side.
  • Scar tissue or plaque under the skin layer of the penis. The plate looks like a solid mass or cloth to the touch.
  • Short penis. Peyronie's disease can shorten the penis.
  • Erectile Dysfunction People with Peyronie's disease have erectile problems and maintain them.
  • Pain in the penis. This pain is felt not only when the penis is erect, but also when the penis is not erect.

Causes of Peyronie's disease
We don't know yet what causes Peyronie's disease. Experts suspect that one of the triggers is a recurrent injury to blood vessels in the penis, for example when exercising or having sexual relations. This injury causes bleeding in the penis and triggers the immune system's response, resulting in the formation of scar tissue. However, these injuries cannot always be remembered by the victims.
Risk factors for Peyronie's disease

A number of factors can inhibit the healing process of injury and trigger the formation of scar tissue in the penis, including:

  • Age. The risk of Peyronie's disease increases with age, especially in men over 55 years.
  • Genetics. Peyronie's disease is more likely to occur in someone with family members who suffer from the disease.
  • Connective tissue disorders. Some people with Peyronie's disease also suffer from Dupuytren contracture, which occurs when hard tissue forms under the palm of the hand and bends the fingers inward.

Diagnosis of Peyronie's disease


To get a diagnosis of Peyronie's disease, the doctor will ask for a patient's medical history, especially those related to a history of penile lesions before the patient suffers from Peyronie's disease. Then, the doctor will do a physical examination by feeling the scar tissue on the patient's penis. If necessary, the doctor will first inject special drugs into the penis to get an erection.

Scar tissue detection can also be done by ultrasonography or radiography. The doctor can also do a biopsy, which involves taking a small sample of tissue from the folded penis for laboratory tests.

Treatment of Peyronie's disease
A number of treatment methods are used to treat Peyronie's disease, including:

drug


Although less effective than surgery, several types of drugs can be used to treat Peyronie's disease. For oral treatment, the doctor will prescribe pentoxifylline for several months to reduce scarring on the patient's penis.

For injectable drugs, interferon or verapamil are drugs that can be used. These drugs reduce scarring on the penis and destroy collagen deposits that cause the penis to bend.

Operation


This procedure will be carried out in conditions of severe Peyronie's disease, for example to make patients unable to have sex. Surgery is not recommended if the condition does not last for one year and the curvature of the penis changes again within 6 months.

The doctor can choose from several available surgical methods, depending on the patient's condition, the location of the scar tissue on the penis and the severity of the symptoms. A number of surgical procedures for Peyronie's disease are:

Application. This procedure stings the side of the penis when there are no scars. Although it can straighten the penis, the penis can also shorten and risk causing erectile dysfunction.

Incision and transplantation. This procedure is done by making one or more incisions in the scar tissue so that the penis can stretch. In some cases, doctors can also remove some scar tissue, and then transplant the hole with the patient's body tissue, body tissue, or synthetic tissue.

This procedure is usually done only on patients with more severe penile curvature. Please note that this procedure can worsen erection problems.

Penile implants. The doctor will implant the implant to replace the penile tissue that is filled with blood during an erection. This procedure is generally performed on patients with Peyronie's disease and also has erectile dysfunction. If necessary, the doctor will combine penile implants with other procedures to correct penile curvature.

Depending on the type of surgery performed, patients can return home after surgery or require hospitalization. Ask your doctor how long you need to rest before continuing your activities. Generally, patients are only allowed to have sex after 4 to 8 weeks postoperatively.

Other treatments that can be used to treat Peyronie's disease include radiation therapy, penile traction or penile traction using special tools, and shock wave therapy called ESST. However, research is still needed on the efficacy and possible side effects resulting from these treatments.
Complications of Peyronie's disease
In addition to stressing the patient and partner, Peyronie's disease can also make the patient helpless, which can lead to an inability to have sex and have children.

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