Prevents aging and increases metabolism by fasting
Benefits of fasting to prevent premature aging
A study shows that the benefits of fasting can prevent the body stay young, live longer, and avoid chronic diseases. This research was published in the journal Molecular Cell.
This research was conducted by Dr. Ming Hui Zou, Director of the Center for Molecular and Translational Medicine at Georgia State University in Atlanta. Zou said that fasting can prevent aging of blood vessels.
He also explained that as we get older, the blood vessels that supply oxygen throughout the body will become the most sensitive and easily damaged old organs. In this study, the research team began to focus on the aging process in blood vessels and how to prevent it.
Well, here, the researchers tested mice as test objects. Where food calorie intake is limited, as do people on an empty stomach. The researchers found that hungry mice in the body produce useful molecules.
Molecules derived from the benefits of fasting are called beta-hydroxybutyrate and can prevent aging in the blood vessels of mice. Beta-hydroxybutyrate is a ketone. Ketones are molecules produced by the liver and used as an energy source when glucose reserves are not available.
The body usually produces ketones during fasting or starvation, during low-carbohydrate diets and after prolonged exercise.
This study also shows that beta-hydroxybutyrate can delay the aging process that occurs in blood vessels. This is certainly good news because the aging process of blood vessels is the root of many chronic diseases, such as heart and blood vessel disease and Alzheimer's disease. If blood vessels can stay young, the risk of this disease will be reduced.
Benefits of fasting increase metabolism
Besides being beneficial in preventing body aging, the benefits of fasting also increase the body's metabolism. Metabolism is a process that the body uses to digest food and convert it into energy.
To determine the benefits of fasting, one study examined 4 volunteers who fasted for 58 hours. Using metabolism, or metabolite measurements, the researchers analyzed complete blood samples during fasting. Indeed, when the human body lacks food, a number of metabolic changes occur.
Usually, when carbohydrates are available from regular meals 3 times a day, the body uses them as fuel. But once the body does not have enough carbohydrates, it will look for energy elsewhere.
In a process called gluconeogenesis, the body will also get glucose from non-carbohydrate sources, such as amino acids.
The researchers discovered the process of gluconeogenesis by assessing levels of certain metabolites in the blood, including carnitine and butyrate in fasting people. In addition, researchers have found an increase in products from the citric acid cycle.
The citric acid cycle occurs in the mitochondria and its function is to release the energy stored in the body. This shows that mitochondria, as a source of energy, work harder than when not fasting.
But this research is still small. To learn more about the effects of fasting on increasing the body's metabolism, the researchers plan to conduct research on a larger scale.
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